Augmenting Ion Trap Mass Spectrometers Using a Frequency Modulated Drift Tube Ion Mobility Spectrometer

Keywords

ion mobility, ion mobility spectrometry, high performance ion mobility spectrometry, ESI, Electrospray Ionization, IMS-MS, Ion mobility mass spectrometry, IMS-MS, High Performance Ion mobility mass spectrometry, ion trap mass spectrometers 

High Performance Ion mobility mass spectrometry (IMS-MS)

High performance IMS-MSHistorically, high pressure ion mobility drift tubes have suffered from low ion duty cycles. 

This paper describes coupling an atmospheric pressure, dual-gate drift tube ion mobility spectrometer (IMS) to a linear ion trap mass spectrometer (LIT-MS) via modulation of the ion beam with a linear frequency chirp. Overall, chirp multiplexing improves ion transmission, lowers analyte detection limits, and improves spectral quality.

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