Have you ever gone through a TSA screening checkpoint and had them wipe your bag or your shoes? They put the wipe in a box, hit a button and get a result in less than a minute. Ever wonder what that box was, or better yet, why that same technology couldn’t be used for analysis in your own lab? At Excellims, we are experts in that technology, which is based on ion mobility spectrometry. Now imagine that in addition to wipes, you could make automated liquid injections with the same electrospray ionization source technology as a mass spec system, get results with comparable resolution to HPLC in the speed of UV, all controlled by a 21 CFR part 11 compliant software package. Cleaning validation, process reaction monitoring, and in vitro release, are all ideal applications.