Excellims

Benefits of High Performance Ion Mobility Spectrometry (HPIMS) for Cleaning Validation

This paper illustrates the benefits of High Performance Ion Mobility Spectrometry (HPIMS) for Cleaning Validation and how it combats the limitation of existing CV methods.

High Performance Ion Mobility Spectrometry (HPIMS) for PAT

This paper summarizes HPIMS applications for PAT, showcasing its utility and value for cleaning validation, reaction monitoring, and fermentation monitoring.

High Performance Ion Mobility Spectrometry (HPIMS) - Applications in Pharmaceutical Manufacturing and Development

This application note summarizes the critical role that high performance ion mobility spectrometry plays in pharmaceutical analyses.

Rapid Synthetic Organic Reaction Analysis Using High Performance Ion Mobility Spectrometry

Multiple reaction monitoring is a critical step in the synthesis of new drug entities. Companies spend significant resources on equipment and new methods to perform this task.

2D Analysis of Petroleum Samples and Other Complex Mixtures by Ion Mobility Mass Spectrometry on Thermo Scientific^TM Mass Spectrometers

2D Analysis of Petroleum Samples and Other Complex Mixtures by Ion Mobility Mass Spectrometry on Thermo Scientific<sup>TM</sup> Mass Spectrometers image

Petroleum samples are inherently complex mixtures containing thousands of molecules that range in structure from linear alkanes to compact asphaltenes. Crude oil analysis by mass spectrometry (MS) results in extremely information rich data.

Cleaning Validation Analysis Made Easy

This webinar introduces ion mobility spectroscopy (IMS) as a GMP-compliant alternative to legacy methods for at-line cleaning verification, such as TOC swab analysis and HPLC.

Measuring Collision Cross‐Sections (CCS) with HPIMS^TM

Measuring Collision Cross‐Sections (CCS) with HPIMS<sup>TM</sup> image

This application note describes how the MA3100 HPIMS is available as a module for Thermo Fisher Scientific Orbitrap and LTQ mass spectrometers (MS), for resolving isomers and isobars that hinder MS‐only methods.

Precision, Linearity, and Limit of Detection of an Electrospray Ionization High Performance Ion Mobility Spectrometer

This study investigates the analytical performance of an electrospray ionization with a high-performance ion mobility spectrometer (ESI-HPIMS) for pharmaceutical drug and forensically relevant compounds.

Evaluation of Using ESI-HPIMS for Surfactants Analysis

In this application note, Excellims’ electrospray ionization high performance ion mobility spectrometer (ESI-HPIMS) is proven to be an effective surfactants test technology, for the analysis of a variety of molecular weights, structures, and functional groups.

ESI-HPIMS for Rapid Screening of Food Contaminants

Identification of chemical contamination of food is critical to ensuring the safety of the food supply. Phthalates have been used as illicit clouding agents in certain food and drinks outside the U.S. This application note describes the benefits of ESI-HPIMS with electrospray ionization for food screening applications.

Characterization of Explosives using Electrospray Ionization High Resolution Ion Mobility Spectrometry

Ion mobility spectrometers are common as an explosive trace detection technology. This application note describes the HPIMS advantages of very high sensitivity, small size, low power consumption, and ambient pressure operation and how they prevent unwanted responses to interfering chemicals.

Edible Oil Identification with HPIMS^TM: a Rapid Method for Analysis

Edible Oil Identification with HPIMS<sup>TM</sup>: a Rapid Method for Analysis image

Chemical contamination of food is a long standing problem. Edible oils are highly complex. Many different lab based techniques have been applied to analyzing edible oils and fatty acids (HPLC, FTIR etc).

Application Notes & White Papers